Press Release

Exelixis Announces March 10 Webcast of Presentation at the Cowen and Company 30th Annual Healthcare Conference

March 4, 2010

SOUTH SAN FRANCISCO, Calif., Mar 04, 2010 (BUSINESS WIRE) -- Exelixis, Inc. (NASDAQ:EXEL) announced today that George A. Scangos, PhD, the company's president and chief executive officer, will present at the Cowen and Company 30th Annual Healthcare Conference at 10:15 a.m. EST / 7:15 a.m. PST on Wednesday, March 10, 2010 in Boston. Dr. Scangos will discuss the company's corporate strategy, development pipeline, financial results and financial outlook.

The event will be webcast and may be accessed in the Event Calendar page under Investors at http://www.exelixis.com.

About Exelixis

Exelixis, Inc. is a development-stage biotechnology company dedicated to the discovery and development of novel small molecule therapeutics for the treatment of cancer and other serious diseases. The company is leveraging its fully integrated drug discovery platform to fuel the growth of its development pipeline, which is primarily focused on cancer. Currently, Exelixis' broad product pipeline includes investigational compounds in phase 3, phase 2, and phase 1 clinical development. Exelixis has established strategic corporate alliances with major pharmaceutical and biotechnology companies, including Bristol-Myers Squibb, sanofi-aventis, GlaxoSmithKline, Genentech (a wholly owned member of the Roche Group), Boehringer Ingelheim, Pfizer Inc., and Daiichi-Sankyo. For more information, please visit the company's web site at http://www.exelixis.com.

Exelixis and the Exelixis logo are registered U.S. trademarks.

SOURCE: Exelixis, Inc.

Exelixis, Inc.
Investor Contacts:
Charles Butler, 650-837-7277
Vice President, Investor Relations and Corporate Communications
cbutler@exelixis.com
or
DeDe Sheel, 650-837-8231
Associate Director, Investor Relations
dsheel@exelixis.com