SOUTH SAN FRANCISCO, Calif., April 28 /PRNewswire-FirstCall/ -- Exelixis, Inc. (Nasdaq: EXEL) will release its first quarter 2008 financial results on Tuesday, May 6, 2008, after the markets close. The announcement will be followed by a live webcast at 2:00 p.m. PT/5:00 p.m. ET, in which Exelixis management will discuss the first quarter financial results and give a general update on the company's financial position and business, including its development pipeline and corporate strategy. The webcast may be accessed in the Event Calendar page under Investors at http://www.exelixis.com.

An archive of this webcast will be available until 8:59 p.m. PT/11:59 p.m. ET on June 6, 2008. Access numbers for this replay are 1-888-286-8010 (domestic) and 1-617-801-6888 (international); the replay passcode number is 37936947.

About Exelixis

Exelixis, Inc. is a development-stage biotechnology company dedicated to the discovery and development of novel small molecule therapeutics for the treatment of cancer and other serious diseases. The company is leveraging its fully integrated drug discovery platform to fuel the growth of its development pipeline, which is primarily focused on cancer. Currently, Exelixis' broad product pipeline includes investigational compounds in phase 2 and phase 1 clinical development. Exelixis has established strategic corporate alliances with major pharmaceutical and biotechnology companies, including GlaxoSmithKline, Bristol-Myers Squibb Company, Genentech, Wyeth Pharmaceuticals and Daiichi-Sankyo. For more information, please visit the company's web site at http://www.exelixis.com.

SOURCE Exelixis, Inc.
CONTACT: Investors, Charles Butler, Senior Director Corporate
Communications & Investor Relations, +1-650-837-7277, cbutler@exelixis.com, or
Media, Soleil Maxwell Harrison, Senior Manager Corporate Communications,
+1-650-837-7012, sharrison@exelixis.com, both of Exelixis, Inc.
Web site: http://www.exelixis.com