Press Release

Exelixis Announces September 8th Webcast of
Presentation at the Stifel Nicolaus Healthcare Conference

September 2, 2011

SOUTH SAN FRANCISCO, Calif., Sep 02, 2011 (BUSINESS WIRE) --

Exelixis, Inc. (NASDAQ:EXEL) announced today that Michael Morrissey, PhD, the company's president and chief executive officer, will present at the Stifel Nicolaus Healthcare Conference at 4:25 p.m. EDT / 1:25 p.m. PDT on Thursday, September 8, 2011, in Boston. During the presentation, Dr. Morrissey will provide a general business update, review the most recent publicly available data for cabozantinib in castration-resistant prostate cancer, and discuss the pivotal trial plans and regulatory strategy for the compound.

The presentation will be webcast and may be accessed in the Event Calendar page under Investors at www.exelixis.com.

About Exelixis

Exelixis, Inc. is a biotechnology company committed to developing small molecule therapeutics for the treatment of cancer. Exelixis is focusing its resources and development efforts exclusively on cabozantinib, its most advanced solely-owned product candidate, in order to maximize the therapeutic and commercial potential of this compound. Exelixis believes cabozantinib has the potential to be a high-quality, differentiated pharmaceutical product that can make a meaningful difference in the lives of patients. Exelixis has also established a portfolio of other novel compounds that it believes have the potential to address serious unmet medical needs. For more information, please visit the company's web site at www.exelixis.com.

SOURCE: Exelixis, Inc.

Exelixis, Inc.
Charles Butler, 650-837-7277
Vice President
Investor Relations & Corporate Communications
cbutler@exelixis.com