Press Release

Exelixis Announces November 29th Webcast of Presentation at the Piper Jaffray Health Care Conference

November 22, 2011

SOUTH SAN FRANCISCO, Calif., Nov 22, 2011 (BUSINESS WIRE) -- Exelixis, Inc. (NASDAQ:EXEL) today announced that Michael M. Morrissey, Ph.D., the company's president and chief executive officer, will present at the Piper Jaffray Health Care Conference at 3:30 p.m. EST / 12:30 p.m. PST on Tuesday, November 29, 2011 in New York. During the presentation, Dr. Morrissey will provide a general business update and review the most recent publicly available data for cabozantinib, including clinical data presented at the AACR-NCI-EORTC meeting earlier this month. He will also discuss the pivotal trial plans and regulatory strategy for the compound.

The presentation will be webcast and may be accessed in the Event Calendar page under Investors at http://www.exelixis.com.

About Exelixis

Exelixis, Inc. is a biotechnology company committed to developing small molecule therapeutics for the treatment of cancer. Exelixis is focusing its proprietary resources and development efforts exclusively on cabozantinib, its most advanced solely-owned product candidate, in order to maximize the therapeutic and commercial potential of this compound. Exelixis believes cabozantinib has the potential to be a high-quality, differentiated pharmaceutical product that can make a meaningful difference in the lives of patients. Exelixis has also established a portfolio of other novel compounds that it believes have the potential to address serious unmet medical needs. For more information, please visit the company's web site at http://www.exelixis.com.

SOURCE: Exelixis, Inc.

Exelixis, Inc.
Charles Butler, 650-837-7277
Vice President, Investor Relations and Corporate Communications
cbutler@exelixis.com