Filed by Exelixis, Inc.
                       Pursuant to Rule 425 under the Securities Act of 1933 and
            Deemed filed under Rule 14d-2 of the Securities Exchange Act of 1934

                                           Subject Company: Genomica Corporation

                                                  Commission File No.: 000-31637




                             SOURCE: EXELIXIS, INC.

                          Thursday, November 29, 2001

                                  Press Release

FOR IMMEDIATE RELEASE

Contact:
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Exelixis,  Inc.                                    Genomica  Corporation
Glen  Sato                                         Dan Hudspeth
Chief Financial Officer                            Chief  Financial  Officer
650-837-7565                                       720-565-4030

     EXELIXIS AND GENOMICA ANNOUNCE COMMENCEMENT OF EXELIXIS EXCHANGE OFFER

SOUTH  SAN  FRANCISCO, CA and BOULDER, CO  -- November 29, 2001 --Exelixis, Inc.
(Nasdaq:  EXEL)  and  Genomica  Corporation  (Nasdaq: GNOM) announced today that
Exelixis,  through  a  wholly  owned  subsidiary,  has  commenced its previously
Announced exchange  offer  for  shares  of  Genomica  common  stock.

Genomica's  board  of  directors  has  unanimously  recommended  that  Genomica
stockholders  accept  the exchange offer.  The exchange ratio of Exelixis common
stock  for outstanding shares of Genomica common stock will be determined by the
following  formula:  a  number  equal  to  the quotient obtained by dividing the
Genomica  common  stock value by the greater of (a) $13.30285 or (b) the average
closing  sales  price  of  Exelixis  common  stock on the Nasdaq National Market
during  the  18  trading-day  period  ending two trading days before the initial
expiration  of  the  exchange  offer.  The  Genomica  common stock value will be
determined  by  dividing  $110  million  by  the  sum of the number of shares of
Genomica  common stock and preferred stock outstanding plus the number of shares
of  Genomica  common  stock  issuable upon the exercise of all outstanding stock
options  and  warrants  with  a  per share exercise price of $5.00 or less.  The
exchange  offer,  if  successful, will be followed by a merger in which Exelixis
will  acquire,  at  the  same  exchange  ratio, the remaining shares of Genomica
common  stock  not  previously  acquired  in  the  exchange  offer.

Exelixis will issue a press release announcing the final exchange ratio and file
that  press  release with the Securities and Exchange Commission.  The offer and
withdrawal rights are scheduled to expire at 12:00 midnight, New York City time,
on  December  27,  2001,  unless  extended.

ABOUT  EXELIXIS
Exelixis,  Inc.  is  a  leading  worldwide genomics-based drug discovery company
focused on product development through its expertise in comparative genomics and
model  system  genetics. An outstanding team of company scientists has developed
multiple  fungal,  nematode,  insect,  plant  and  vertebrate  genetic  systems.
Exelixis'  proprietary  model  systems  and  comparative  genomics  technologies
address  gene  function  by  using  biologically  relevant  functional  genomics
information  very  early  on  in  the  process  to  rapidly,  efficiently  and
cost-effectively  translate  sequence  data  to  knowledge about the function of
genes  and the proteins that they encode. The company has a significant internal
cancer  discovery  and  drug  development  program,  through  which  a number of
compounds  are  expected  to complete screening by the end of the year. Exelixis
believes  that  its  technology  is  broadly  applicable  to  all  life  science
industries, including pharmaceutical, diagnostic, agricultural biotechnology and
animal  health  and  the  company  has  active  collaborations  with  Aventis
CropScience,  Bayer,  Bristol-Myers  Squibb,  Elan  Pharmaceuticals,  Pharmacia,
Protein  Design  Labs,  Scios and Dow AgroSciences, and is building its internal
development  program in the area of oncology. For more information, please visit
the  Exelixis'  web  site  at  http://www.Exelixis.com/.
                               ------------------------

ABOUT  GENOMICA
Genomica  Corporation  develops  and markets software products and services that
enable  pharmaceutical  and  biotechnology  researchers  to  accelerate the drug
discovery  and  development  process.  Genomica's  customers  include  leading
genomics-based  research  organizations  such  as  AstraZeneca, GlaxoSmithKline,
Aventis and the National Cancer Institute. Genomica also has strategic alliances
with  Applied  Biosystems  and  Celera  Genomics.  For additional information on
Genomica,  please  visit  its  website,  at  http://www.Genomica.com.
                                             -----------------------

ADDITIONAL  INFORMATION
Exelixis  has  filed a Schedule TO and a Registration Statement on Form S-4, and
Genomica  has  filed  a  Solicitation/Recommendation Statement on Schedule 14D-9
with  the  Securities  and  Exchange  Commission.  A Preliminary Prospectus, the
Schedule  14D-9  and  related  tender  offer  materials  have  been  mailed  to
stockholders  of  Genomica.  These documents contain important information about
the  transaction.  Investors  and  security  holders  are  urged  to  read these
documents  carefully. Investors and security holders will be able to obtain free
copies  of these documents through the website maintained by the U.S. Securities
and  Exchange  Commission  at http://www.sec.gov. The Preliminary Prospectus and
related  other  tender  offer  documents  may also be obtained for free from the
parties.

In  addition  to the filings mentioned above, each of Exelixis and Genomica file
annual,  quarterly  and  special reports, proxy statements and other information
with  the Securities and Exchange Commission. You may read and copy any reports,
statements  or other information filed by Exelixis or Genomica at the SEC public
reference  room  at  450 Fifth Street, N.W., Washington, D.C. 20549 or at any of
the  Commission's  other  public  reference rooms in New York, N.Y. and Chicago,
Ill.  Please  call  the  Securities  and Exchange Commission at 800-SEC-0330 for
further  information  on  the  public  reference  rooms. Exelixis and Genomica's
respective  filings  with  the  Securities  and  Exchange  Commission  are  also
available  to  the public from commercial document-retrieval services and at the
website  maintained  by  the  commission  at  http://www.sec.gov.
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