Filed by Exelixis, Inc.
                       Pursuant to Rule 425 under the Securities Act of 1933 and
            Deemed filed under Rule 14d-2 of the Securities Exchange Act of 1934

                                           Subject Company: Genomica Corporation

                                                  Commission File No.: 000-31637




                             SOURCE: EXELIXIS, INC.

                            Tuesday December 18, 2001

                                  Press Release

Contact:
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Exelixis, Inc.                                   Genomica Corporation
Glen Sato                                        Dan Hudspeth
Chief Financial Officer                          Chief Financial Officer
(650)837-7565                                    (720) 565-4030

 EXELIXIS ADJUSTS INITIAL GENOMICA EXCHANGE OFFERING PERIOD DATE TO ACCOUNT FOR
                                 FEDERAL HOLIDAY

- - Initial Offering Period to Expire on December 28 and Exchange Ratio to be Set
                               as of December 26 -

SOUTH  SAN  FRANCISCO,  CA -- December 18, 2001 -- Exelixis, Inc. (Nasdaq: EXEL)
and Genomica Corporation (Nasdaq: GNOM) announced today that due to an Executive
Order authorizing the closure of most federal agencies on December 24, 2001, the
initial  offering  period  for the exchange offer made by Exelixis for shares of
common  stock  of Genomica will expire at 12:00 midnight, New York City time, on
Friday,  December  28, 2001, rather than at 12:00 midnight on Thursday, December
27,  2001,  as  previously  announced.

On  December 5, 2001, President Bush issued an Executive Order providing for the
closing  of all executive branch departments and agencies of the U.S. government
on  December  24,  2001.  As  a  result  of  this Executive Order, the rules and
provisions  of  the Securities Exchange Act of 1934 governing the conduct of the
Exelixis  exchange  offer require Exelixis to extend the initial offering period
for  the  exchange  offer  for  Genomica  stock by one day.  In addition, the 18
trading-day  period ending two trading days before the initial expiration of the
exchange  offer that will be used to calculate the final exchange ratio will now
end on December 26, 2001, rather than on December 24, 2001.  Exelixis will issue
a  press  release  following  the  close  of  market on that date announcing the
exchange  ratio  and  file  that  press release with the Securities and Exchange
Commission.  Genomica  stockholders  can  also call Exelixis' information agent,
Mellon  Investor  Services  LLC, at any time toll free at (866) 323-8159 for the
average  closing  sales price for the preceding 18 trading days and the exchange
ratio  that  would  be  in  effect  based  on  that  price.

Exelixis  has  filed  an amendment with the SEC to its Registration Statement on
Form  S-4  relating  to  shares  of  Exelixis  common  stock to be issued in the
exchange  offer  through  Bluegreen  Acquisition  Sub,  Inc.,  a  wholly  owned
subsidiary  of  Exelixis.  Among  the  amendments  to  Exelixis'  Registration
Statement  are revisions to reflect the extension of the initial offering period
for the exchange offer by one day.  Genomica stockholders are urged to carefully
read  the  Preliminary  Prospectus and the Solicitation/Recommendation statement
previously  filed  with  the  SEC  and  any  and  all  amendments  thereto.

ABOUT  EXELIXIS
Exelixis,  Inc.  is  a  leading  worldwide genomics-based drug discovery company
focused on product development through its expertise in comparative genomics and
model  system genetics.  An outstanding team of company scientists has developed
multiple  fungal,  nematode,  insect,  plant  and  vertebrate  genetic  systems.
Exelixis'  proprietary  model  systems  and  comparative  genomics  technologies
address  gene  function  by  using  biologically  relevant  functional  genomics
information  very  early  on  in  the  process  to  rapidly,  efficiently  and
cost-effectively  translate  sequence  data  to  knowledge about the function of
genes and the proteins that they encode.  The company has a significant internal
cancer  discovery  and  drug  development  program,  through  which  a number of
compounds  are  expected to complete screening by the end of the year.  Exelixis
believes  that  its  technology  is  broadly  applicable  to  all  life  science
industries, including pharmaceutical, diagnostic, agricultural biotechnology and
animal  health  and  the  company  has  active  collaborations  with  Aventis
CropScience,  Bayer,  Bristol-Myers  Squibb,  Elan  Pharmaceuticals,  Pharmacia,
Protein  Design  Labs,  Scios and Dow AgroSciences, and is building its internal
development program in the area of oncology.  For more information, please visit
the  Exelixis'  web  site  at  http://www.Exelixis.com/.
                               ------------------------

ABOUT  GENOMICA
Genomica  Corporation  develops  and markets software products and services that
enable  pharmaceutical  and  biotechnology  researchers  to  accelerate the drug
discovery  and  development  process.  Genomica's  customers  include  leading
genomics-based  research  organizations  such  as  AstraZeneca, GlaxoSmithKline,
Aventis  and  the  National  Cancer  Institute.  Genomica  also  has  strategic
alliances  with  Applied  Biosystems  and  Celera  Genomics.  For  additional
information  on  Genomica, please visit its website, at http://www.Genomica.com.
                                                        -----------------------

ADDITIONAL  INFORMATION
The  Genomica  Corporation  board  of directors has unanimously recommended that
Genomica stockholders accept the exchange offer.  The exchange ratio of Exelixis
common  stock for outstanding shares of Genomica common stock will be determined
by  the  following formula:  a number equal to the quotient obtained by dividing
the  Genomica  common  stock  value  by  the greater of (a) $13.30285 or (b) the
average  closing  sales  price  of  Exelixis common stock on the Nasdaq National
Market  during  the  18  trading-day  period  ending two trading days before the
initial  expiration of the exchange offer.  The Genomica common stock value will
be  determined  by  dividing  $110 million by the sum of the number of shares of
Genomica  common stock and preferred stock outstanding plus the number of shares
of  Genomica  common  stock  issuable upon the exercise of all outstanding stock
options  and  warrants  with  a  per share exercise price of $5.00 or less.  The
exchange  offer,  if  successful, will be followed by a merger in which Exelixis
will  acquire,  at  the  same  exchange  ratio, the remaining shares of Genomica
common  stock  not  previously  acquired  in  the  exchange  offer.

Exelixis  has  filed a Schedule TO and a Registration Statement on Form S-4, and
Genomica  has  filed  a  Solicitation/Recommendation Statement on Schedule 14D-9
with  the  Securities  and  Exchange  Commission.  A Preliminary Prospectus, the
Schedule 14D-9 and related tender offer materials were mailed to stockholders of
Genomica  on  November  29, 2001.  These documents contain important information
about  the  transaction.  Investors  and security holders are urged to carefully
read  these  documents,  and  any  and  all  amendments  thereto.  Investors and
security  holders  will be able to obtain free copies of these documents through
the  website  maintained  by  the  U.S.  Securities  and  Exchange Commission at
http://www.sec.gov.  The  Preliminary  Prospectus and related other tender offer
documents  may  also  be  obtained  for  free  from  the  parties.

In  addition  to the filings mentioned above, each of Exelixis and Genomica file
annual,  quarterly  and  special reports, proxy statements and other information
with the Securities and Exchange Commission.  You may read and copy any reports,
statements  or other information filed by Exelixis or Genomica at the SEC public
reference  room  at  450 Fifth Street, N.W., Washington, D.C. 20549 or at any of
the  Commission's  other  public  reference rooms in New York, N.Y. and Chicago,
Ill.  Please  call  the  Securities  and Exchange Commission at 800-SEC-0330 for
further  information  on  the  public  reference rooms.  Exelixis and Genomica's
respective  filings  with  the  Securities  and  Exchange  Commission  are  also
available  to  the public from commercial document-retrieval services and at the
website  maintained  by  the  commission  at  http://www.sec.gov.
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