Filed by Exelixis, Inc.
                       Pursuant to Rule 425 under the Securities Act of 1933 and
            Deemed filed under Rule 14d-2 of the Securities Exchange Act of 1934

                                           Subject Company: Genomica Corporation

                                                  Commission File No.: 000-31637




                             SOURCE: EXELIXIS, INC.

                            Wednesday January 2, 2002

                                  Press Release

Contact:
- -------

Exelixis,  Inc.
Glen  Sato
Chief  Financial  Officer
(650)  837-7565

              EXELIXIS ANNOUNCES CLOSING OF GENOMICA EXCHANGE OFFER

    - Genomica Stockholders Tender in Excess of 90% of Shares Outstanding as of
                               December 28, 2001 -

SOUTH SAN FRANCISCO, CA - January 2, 2002 -- Exelixis, Inc. (Nasdaq: EXEL) today
announced  the  closing of the exchange offer for shares of Genomica Corporation
(Nasdaq:  GNOM).  The  final  exchange  ratio of shares of Genomica common stock
will  result  in  conversion of each share of Genomica common stock into 0.28309
shares  of  Exelixis  common  stock.  The exchange offer expired as scheduled at
midnight  on  December  28,  2001.

Based  on  information  provided by the exchange agent for the Exelixis exchange
offer,  approximately  23,026,086  shares  of Genomica common stock were validly
tendered  during  the  offering  period,  including  8,748,708  shares that were
subject  to  notices of guaranteed delivery. This total represents approximately
94.41%  of  the  total  outstanding  shares  of  Genomica  common  stock.

Before  the  end of January 2002, Exelixis expects to initiate a merger in which
Exelixis  will acquire, at the same 0.28309 exchange ratio, the remaining shares
of  Genomica  common  stock  not  previously  acquired  in  the  exchange offer.
Exelixis  expects  to  complete  the  merger before the end of February 2002.  A
total  of approximately 6,904,452 shares of Exelixis common stock will be issued
for  all  of  the  outstanding  shares of Genomica.  Following the filing of the
certificate  of  merger,  Genomica  will  continue  to  exist  as a wholly owned
subsidiary  of  Exelixis.

The  final  exchange  ratio  of  Exelixis common stock for outstanding shares of
Genomica common stock was determined by the following formula:  (a) $110 million
divided  by  24,460,254  (which  represents  the  sum of the number of shares of
Genomica  common stock and preferred stock outstanding plus the number of shares
of  Genomica  common  stock  issuable upon the exercise of all outstanding stock
options  and  warrants with a per share exercise price of $5.00 or less) divided
by  (b)  $15.88556 (which was the average closing sales price of Exelixis common
stock  on  the  Nasdaq  National  Market  for  the  18 trading-day period ending
December  26,  2001).


ABOUT  EXELIXIS
Exelixis,  Inc.  is  a  leading  worldwide genomics-based drug discovery company
focused on product development through its expertise in comparative genomics and
model  system genetics.  An outstanding team of company scientists has developed
multiple  fungal,  nematode,  insect,  plant  and  vertebrate  genetic  systems.
Exelixis'  proprietary  model  systems  and  comparative  genomics  technologies
address  gene  function  by  using  biologically  relevant  functional  genomics
information  very  early  on  in  the  process  to  rapidly,  efficiently  and
cost-effectively  translate  sequence  data  to  knowledge about the function of
genes and the proteins that they encode.  The company has a significant internal
cancer  discovery  and  drug  development  program,  through  which  a number of
compounds  are  expected to complete screening by the end of the year.  Exelixis
believes  that  its  technology  is  broadly  applicable  to  all  life  science
industries, including pharmaceutical, diagnostic, agricultural biotechnology and
animal  health  and  the  company  has  active  collaborations  with  Aventis
CropScience,  Bayer,  Bristol-Myers  Squibb,  Elan  Pharmaceuticals,  Pharmacia,
Protein  Design  Labs,  Scios and Dow AgroSciences, and is building its internal
development program in the area of oncology.  For more information, please visit
the  Exelixis'  web  site  at  http://www.Exelixis.com/.
                               ------------------------


ADDITIONAL  INFORMATION
Genomica  stockholders who did not tender their shares in the exchange offer are
urged  to  carefully  read  the  Preliminary  Prospectus  and  the
Solicitation/Recommendation  statement previously filed with the SEC and any and
all  amendments  thereto.

The  information  provided  in  this  press  release  contains  forward-looking
statements  regarding  Exelixis'  proposed  acquisition of Genomica that involve
risks  and  uncertainties,  including  statements  regarding  the  timing of the
transaction  and  the delivery of shares for which notice of guaranteed delivery
has  been  received.  Actual results may not be realized, or may vary materially
from  results that may be discussed in these forward-looking statements. Factors
that  may  affect  actual  results  include the risks inherent in completing the
acquisition  of  Genomica  on  a  timely  basis,  if at all, and the other risks
detailed  from  time  to time in its  periodic reports filed with the Securities
and  Exchange  Commission, including but not limited to Exelixis' report on Form
10-K  for  the  fiscal  year ended December 31, 2000 and its other reports filed
with  the  SEC  from  time  to  time.  The  information in this press release is
current  as  of  its release date.  Exelixis assumes no responsibility to update
the  information.

Exelixis  and the Exelixis logo are registered U.S. trademarks of Exelixis, Inc.