0000001 - Document - Cover Page link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - CONSOLIDATED BALANCE SHEETS link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - CONSOLIDATED BALANCE SHEETS (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - CONSOLIDATED STATEMENTS OF INCOME link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - CONSOLIDATED STATEMENTS OF COMPREHENSIVE INCOME (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY link:presentationLink link:calculationLink link:definitionLink 9952157 - Statement - CONSOLIDATED STATEMENTS OF CASH FLOWS link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Organization and Summary of Significant Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Segment Reporting link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Revenues link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Collaboration Agreements And Business Development Activities link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Cash and Marketable Securities link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Inventory link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Property and Equipment link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Stockholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Provision For Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Net Income Per Share link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Restructuring link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Organization and Summary of Significant Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Segment Reporting (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Revenues (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Collaboration Agreements And Business Development Activities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Cash and Marketable Securities (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Inventory (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Property and Equipment (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Stockholders’ Equity (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Provision For Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Net Income Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Commitments and Contingencies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Restructuring (Tables) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Organization and Summary of Significant Accounting Policies (Details) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Segment Reporting - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Segment Reporting - Segment and Consolidated Net Income (Details) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Revenues - Revenues by Disaggregated Category (Details) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Revenues - Net Product Revenues Disaggregated by Product (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Revenues - Revenues Disaggregated by Significant Customer (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Revenues - Revenues Disaggregated by Geographic Region (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Revenues - Activities and Ending Reserve Balances for Significant Categories of Discounts and Allowances (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Revenues - Contract Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Collaboration Agreements And Business Development Activities - Ipsen Collaboration Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Ipsen (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Collaboration Agreements And Business Development Activities - Takeda Collaboration Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Collaboration Agreements And Business Development Activities - Collaboration Revenues under the Collaboration Agreement with Takeda (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Collaboration Agreements And Business Development Activities - Royalty Pharma (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Collaboration Agreements And Business Development Activities - Other Collaborations Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Cash and Marketable Securities - Investments by Security Type (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Cash and Marketable Securities - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Cash and Marketable Securities - Fair Value and Gross Unrealized Losses of Investments Available-for-Sale in an Unrealized Loss Position (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Cash and Marketable Securities - Fair Value of Cash Equivalents and Investments by Contractual Maturity (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Fair Value Measurements (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Fair Value Measurements - Narratives (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Inventory (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Property and Equipment - Schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Property and Equipment - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Stockholders’ Equity - Schedule of Allocated Employee Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Stockholders’ Equity - Schedule of Employee Service Share - Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Stockholders’ Equity - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Stockholders’ Equity - Weighted Average Grant Date Fair Value (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Stockholders’ Equity - Schedule of Fair Value of Employee Share-Based Payments Awards ESPP Assumptions and Weighted Average Fair Values (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Stockholders’ Equity - Summary of All Stock Option Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Stockholders’ Equity - Summary of All RSU & PSU Activity (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Stockholders’ Equity - Estimated Grant-Date Fair Value (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Provision For Income Taxes - Components of Income Tax Expense (Benefit) (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Provision For Income Taxes - Schedule of Reconciliation of Income Taxes at the Statutory Federal Income Tax Rate to Net Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955558 - Disclosure - Provision For Income Taxes - Schedule of Deferred Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955559 - Disclosure - Provision For Income Taxes - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955560 - Disclosure - Provision For Income Taxes - Schedule of Unrecognized Tax Benefits (Details) link:presentationLink link:calculationLink link:definitionLink 9955561 - Disclosure - Net Income Per Share - Computation of Basic and Diluted Net Income Per Share (Details) link:presentationLink link:calculationLink link:definitionLink 9955562 - Disclosure - Net Income Per Share - Potentially Dilutive Shares of Common Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9955563 - Disclosure - Commitments and Contingencies - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955564 - Disclosure - Commitments and Contingencies - Balance Sheet Classification of Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955565 - Disclosure - Commitments and Contingencies - Components of Lease Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955566 - Disclosure - Commitments and Contingencies - Lease Cash Flow And Other Information Disclosure (Details) link:presentationLink link:calculationLink link:definitionLink 9955567 - Disclosure - Commitments and Contingencies - Maturities of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955567 - Disclosure - Commitments and Contingencies - Maturities of Operating Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955568 - Disclosure - Restructuring - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955569 - Disclosure - Restructuring - Restructuring Activities (Details) link:presentationLink link:calculationLink link:definitionLink